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1. Introduction 1.1 Background and Motivation 1.2 Research Objectives 1.3 Structure of the Study 2. Gut Microbiota: An Overview 2.1 Definition and Composition 2.2 Functions and Significance 2.3 Methods of Analysis 3. Neuroinflammation in Neurodegenerative Diseases 3.1 Definition and Mechanisms 3.2 Common Neurodegenerative Conditions 3.3 Neuroinflammation Biomarkers 4. Gut-Brain Axis 4.1 Concept and Components 4.2 Pathways of Interaction 4.3 Role in Disease Progression 5. Impact of Gut Microbiota on Brain 5.1 Influence on Neuroinflammation 5.2 Microbial Metabolites and Brain Function 5.3 Case Studies of Relevant Interactions 6. Mechanisms Linking Microbiota and Neuroinflammation 6.1 Immunomodulatory Effects 6.2 Neurotransmitter Modulation 6.3 Integrity of the Blood-Brain Barrier 7. Therapeutic Implications and Interventions 7.1 Probiotics and Prebiotics 7.2 Dietary Modifications 7.3 Future Therapies and Trials 8. Conclusion and Future Directions 8.1 Summary of Findings 8.2 Limitations of Current Research 8.3 Proposed Research Directions
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