Investigating the Role of Microglia in Neuroinflammatory Processes of Neurodegenerative Diseases

1. Introduction 2. Neuroinflammatory Processes in Neurodegenerative Diseases 2.1 Defining Neuroinflammation 2.2 Overview of Neurodegenerative Diseases 2.3 Importance of Neuroinflammation 2.4 Connection Between Inflammation and Neurodegeneration 3. Role of Microglia in the Brain 3.1 Microglial Cells Overview 3.2 Microglial Activation Mechanisms 3.3 Microglia in Healthy Brain Function 4. Microglia-Mediated Neuroinflammation 4.1 Microglial Response to Injury 4.2 Cytokine Release and Effects 4.3 Microglial Modulation of Synaptic Function 5. Microglia in Alzheimer’s Disease 5.1 Microglial Interaction with Amyloid Plaques 5.2 Role in Tau Pathology 5.3 Targeting Microglia in Therapy 6. Microglia and Parkinson’s Disease 6.1 Microglial Influence on Dopaminergic Neurons 6.2 Inflammatory Processes in Parkinson’s 6.3 Therapeutic Modulation of Microglia 7. Therapeutic Implications 7.1 Anti-inflammatory Treatments 7.2 Microglia-targeted Therapies 7.3 Future Directions in Neurodegeneration Treatment 8. Conclusion 9. Future Research Directions 9.1 Unresolved Questions 9.2 Potential Research Methods 9.3 Anticipated Challenges and Solutions