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1. Introduction 2. Overview of Epigenetic Modifications 2.1 Definition and Mechanisms 2.2 Types of Epigenetic Modifications 2.3 Impact on Gene Expression 3. Neurodegenerative Diseases: A General Perspective 3.1 Definition and Characteristics 3.2 Prevalence and Importance 3.3 Current Treatment Strategies 4. Biochemical Pathways in Neurodegeneration 4.1 Oxidative Stress and Inflammation 4.2 Protein Misfolding and Aggregation 4.3 Mitochondrial Dysfunction 5. Epigenetic Modifications in Neurodegenerative Diseases 5.1 Influence on Alzheimer's Disease 5.2 Role in Parkinson's Disease 5.3 Impact on Huntington's Disease 6. Diagnostic and Therapeutic Implications 6.1 Epigenetic Biomarkers 6.2 Epigenetic Therapies 6.3 Challenges and Limitations 7. Research Methodologies 7.1 Analytical Techniques 7.2 In Vitro and In Vivo Models 7.3 Data Analysis Approaches 8. Future Directions and Conclusion 8.1 Emerging Trends in Research 8.2 Potential for Clinical Applications 8.3 Summary and Final Thoughts
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