Investigating the Role of RNA Modifications in Cellular Stress Response Mechanisms

1. Introduction 2. Overview of RNA Modifications 2.1 Types of RNA Modifications 2.2 Biological Functions of RNA Modifications 2.3 Detection and Analysis Techniques 3. Cellular Stress Response Mechanisms 3.1 Definition and Types of Stress 3.2 Key Pathways in Stress Response 3.3 Role of RNA in Stress Response 4. RNA Modifications Regulating Stress 4.1 Impact on Protein Translation 4.2 Modifications Affecting RNA Stability 4.3 Interaction with Stress Granules 5. Specific Modified Nucleotides 5.1 m6A and its Role 5.2 Pseudouridine in Stress Situations 5.3 5-methylcytosine Contribution 6. Experimental Approaches 6.1 Recent Advances in Methodologies 6.2 Model Systems Used in Research 6.3 Challenges and Limitations 7. Case Studies 7.1 RNA Modifications in Cancer Stress Response 7.2 Neurological Disorders and RNA Modifications 7.3 Plant Stress and RNA Modifications 8. Future Directions and Conclusions 8.1 Potential Therapeutic Interventions 8.2 Emerging Research Questions 8.3 Summary of Key Insights